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HPC has been implemented in many sequence bioinformatics software tools. The HiCanu112, MDBG113, wtdbg275, shasta114 assemblers all use HPC under the hood to provide better assemblies, and HPC was used to assemble the complete human genome sequence4. The first published usage of HPC, was actually in the CABOG assembler115 developed for pyrosequencing reads. HPC has also been implemented for other tasks, like clustering116, long read error correction with LSC117 and LSCPlus118, alignment with minimap2119 and winnowmap2120, or specific analysis pipelines for satellite tandem repeats121.